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We are seeking an experienced and solutions-focused Clinical Operations Manager to lead the epilepsy clinical trials portfolio at the National Hospital for Neurology and Neurosurgery (NHNN). This is an excellent opportunity for a motivated leader with strong operational, financial, and governance expertise to shape the future of epilepsy research across two internationally recognised sites.
Based across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire), you will oversee study setup, trial delivery, and financial sustainability of both commercial and non-commercial trials, working closely with Principal Investigators, Senior Research Nurses, and the UCL/UCLH Joint Research Office. This is a strategic yet hands-on role where you will strengthen trial capacity, accelerate setup timelines, and ensure high-quality, compliant delivery. You will also line manage members of the research delivery team, supporting staff recruitment, development, and workload allocation. Acting as a key contact for investigators, sponsors, CROs, and regulators, you will represent UCLH as a leading site for epilepsy research.
The ideal candidate will combine leadership with problem-solving skills, thrive in collaboration, and be motivated to drive innovation in clinical research. You will ensure studies are delivered safely, efficiently, and in line with GCP and regulatory requirements across both locations.
As Clinical Operations Manager, you will lead the delivery of a diverse portfolio of epilepsy clinical trials across NHNN Queen Square (London) and the Chalfont Centre for Epilepsy (Buckinghamshire). You will take responsibility for driving trial set-up, monitoring progress, and ensuring studies are delivered safely, on time, and to the highest regulatory standards.
You will line manage research nurses and guide the wider research delivery team, supporting recruitment, training, and development to build a motivated and skilled workforce. A key part of your role will be strengthening collaboration with investigators, industry partners, and regulators, while ensuring the financial sustainability of the portfolio through accurate and timely income recovery.
This is a role for someone who thrives on leadership and problem-solving. Whether streamlining trial processes, guiding staff, or representing UCLH at national and industry forums, you will be central to advancing research that improves the lives of people with epilepsy.
University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
We provide first-class acute and specialist services across eight sites:
University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
National Hospital for Neurology and Neurosurgery
Royal National ENT and Eastman Dental Hospitals
University College Hospital Grafton Way Building
Royal London Hospital for Integrated Medicine
University College Hospital Macmillan Cancer Centre
The Hospital for Tropical Diseases
University College Hospital at Westmoreland Street
We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.
For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.
The post holder will be employed by the Clinical Department of Epilepsy at University College Hospitals Foundation Trust.
We are offering:
• A job in a motivated and highly effective friendly team
• A supportive training and development environment
The post is a fixed term 12-month contract funded by the BRC. There is potential for this FTC to be extended in the future.
LOCATION: The role is split across both sites (NHNN and Chalfont) with days of attendance at each site to be agreed with supervisor based on service needs. Some remote and flexible working will be supported in line with team requirements.
INTERVIEW: A 5-10minute presentation will be required for the interview. The topic will be shared with applicants at time of shortlisting.
Come and be a part of the best NHS trust in England to work for, according to our staff*
* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.
UCLH recognises the benefits of flexible working for staff – To find out more, visit: Flexible working.
To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?
At UCLH, we have a real ‘One Team’ ethos, and our values – safety, kindness, teamwork and improving, are central to the way we work. This is supported by our staff, who voted us as the #1 NHS Acute Trust to work for in the whole of England.
At UCLH we take equality of opportunity seriously and are committed to being a diverse and inclusive employer, with a culture that creates a real sense of belonging and trust. It is our fundamental aim, to recruit, retain and promote a diverse mix of people who are representative of our local communities. Applications are encouraged from candidates of all backgrounds, cultures, and perspectives to support our world class research, innovation and creativity.
UCLH recognises the benefits of flexible working for staff and has a dedicated policy which allows staff to apply for flexible working right from the beginning of employment. For more information please go to: https://www.uclh.nhs.uk/work-with-us/why-choose-uclh/flexible-working.
We offer our permanent staff an interest free season ticket loan for travel, all our staff have access to free independent and confidential support, large retail discounts, a staff discount platform, cycle to work scheme and on-site accommodation to name a few.
Additionally, UCLH Arts and Heritage’s staff wellbeing programme, Creative Comfort, offers a variety of ways to engage with the arts as a member of UCLH staff. You can try out the weekly choir, weekly art club and join the Culture Club for exclusive access to free and discounted tickets for opera, exhibitions, theatre and more.
We recognise, reward and thank colleagues by nominating them for our annual Celebrating Excellence Awards, which are funded by UCLH Charity.
We are also members of www.mytrustbenefits.co.uk/ which offers discounts on high street retail stores, offers on travel deals, and also to take advantage of cash back schemes.
This vacancy may close before the current listed closing date. You are advised not to delay submitting your completed application.
Please note that all correspondence regarding your application will be via email. The emails will be sent to you via TRAC.jobs and not via NHS Jobs, we encourage you to check your inbox regularly.
Please note that if you are at present in a training position on the 2016 new junior doctor’s contract and are applying for a Trust doctor role your salary will not be pay protected.
You will be placed on the appropriate point of the Trust Doctor pay scale based on your previous experience.
Please note that if you have not heard from us within 3 weeks of the closing date of the advert to assume that you have not been shortlisted on this occasion.
The Trust uses electronic new starter forms on Trac to collect personal details. Information collected is securely stored and used to set up the employee record on the ESR HR system.
For further support on submitting an application please refer to the NLPSS Applicant Toolkit: https://royalfree.pagetiger.com/cuuomnr/1